About the M‑PACT Study
Military and Veterans PTSD Adaptive Platform Clinical Trial
The study is investigating how study medications can help with PTSD. It will be testing multiple medications to see how well each of them works to treat posttraumatic stress disorder.
The M-PACT study is unique in that it will utilize an adaptive platform design. In this study, we’ll be testing multiple medications to see if they improve PTSD symptoms. The innovative study design increases your chances of receiving active medication instead of placebo, and allows you to potentially receive more than one medication.
Here’s how it works:
If eligible, you’ll be randomly assigned to one of multiple treatment groups for 20 weeks.
Depending on your initial group and response, you might be eligible to receive a different medication in a different study group. This could extend your participation beyond 20 weeks.
You can be compensated $575 or more in each study group.
The Department of Defense and Clinical Research
The Department of Defense (DOD) is a strong supporter of clinical research, particularly studies that benefit the health and well-being of both active military personnel and veterans. The DOD funds innovative clinical trials that address a wide range of health conditions, from combat injuries and PTSD to chronic illness.
Military service members and veterans are uniquely positioned to contribute to medical advancements. Your experiences and resilience make you a valuable participant in clinical research. However, it is understandable that some may have reservations. The DOD prioritizes ethical research practices and ensures all trials are reviewed by independent boards to protect participants’ safety and privacy.
If you are considering enrolling in the M‑PACT study, open communication with your doctor is key. They can help you understand the specifics of the research and determine if it aligns with your health goals. The DOD is committed to providing resources and information to empower informed decisions about participation in clinical research.
Where We Are
Locations
Current research site locations are listed below and more may be added at any time.
| Birmingham, Alabama | Bethesda, Maryland |
| Phoenix, Arizona | Williamsville, New York |
| San Francisco, California | Cincinnati, Ohio |
| West Haven, Connecticut | Charleston, South Carolina |
| Miami, Florida | Lackland AFB, Texas |
| Atlanta, Georgia | Fort Belvoir, Virginia |
| Honolulu, Hawaii |
Birmingham, Alabama
Phoenix, Arizona
San Francisco, California
West Haven, Connecticut
Miami, Florida
Atlanta, Georgia
Honolulu, Hawaii
Bethesda, Maryland
Williamsville, New York
Cincinnati, Ohio
Charleston, South Carolina
Lackland AFB, Texas
Fort Belvoir, Virginia
Phoenix, Arizona
San Francisco, California
West Haven, Connecticut
Miami, Florida
Atlanta, Georgia
Honolulu, Hawaii
Bethesda, Maryland
Williamsville, New York
Cincinnati, Ohio
Charleston, South Carolina
Lackland AFB, Texas
Fort Belvoir, Virginia